HEALTH: NY Times Latest to Mislead Public on New Ivermectin Study • Children’s Health Defense

https://childrenshealthdefense.org/defender/ny-times-mislead-public-ivermectin-study/?utm_source=salsa&eType=EmailBlastContent&eId=a00a2e8c-3156-4f4b-85a8-a703c029bc06

NY Times Latest to Mislead Public on New Ivermectin Study • Children’s Health Defense

  • The New York Times on Wednesday sent an email to subscribers titled: “Breaking News: Ivermectin failed as a Covid treatment . . .” The Times was referring to a study in the New England Journal of Medicine, covered March 18 by The Wall Street Journal. In both cases, the newspapers failed to provide an accurate critical analysis of the study.

By Madhava Setty, M.D.

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Rather than pounding the final nail in the coffin around ivermectin’s utility in treating COVID, the NEJM study raises more questions.

  • What would the effect have been if a higher dose shown to be effective were administered?
  • What would be the benefit of this medicine in patients with no risk factors?
  • How statistically significant would the results have been if more participants were enrolled?
  • Why weren’t more participants enrolled as the study progressed given the emerging benefit of the drug and the absence of adverse events?
  • Why did the investigators define a primary outcome with such different real-world implications (ER visits vs hospitalizations)?
  • With less than 50% of the placebo arm adhering to the study protocol, why were their outcomes included in the analysis?
  • What effect did vaccination status have on outcome? If this is the primary means endorsed to prevent hospitalization, why wasn’t vaccination status mentioned as a confounder?
  • Did the investigators choose to limit the study as it became clear that an Ivermectin benefit would be too big to ignore?

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​Heaven forbid there would be a real test because it might “embarrass” the experts!

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HEALTH: I guess DJT45 was correct about Hydroxychloroquine?

https://articles.mercola.com/sites/articles/archive/2021/10/17/hydroxychloroquine-for-covid.aspx?ui=f9839516412491bb1e06c9e47058c6fb81b9b9b6acedf03e65e93dfdb263c1b9&sd=20210317&cid_source=dnl&cid_medium=email&cid_content=art3HL&cid=20211017&mid=DM1020578&rid=1295221378

NY Doctor Proved Everyone Wrong About Hydroxychloroquine
Analysis by Dr. Joseph Mercola October 17, 2021

  • As early as March 2020, Dr. Vladimir Zelenko boasted a near-100% success rate treating COVID-19 patients with hydroxychloroquine (HCQ), azithromycin and zinc sulfate for five days
  • Zelenko has now treated 3,000 patients with COVID-19 symptoms and only three high-risk patients have died
  • Misinformation and outright lies were spun about HCQ, including fabricated research, in an apparent effort to suppress and prevent widespread use
  • Early treatment is crucial. During the first five days of SARS-CoV-2 infection, the viral load remains fairly steady. Around Day 5, it exponentially increases, potentially overwhelming your immune system. To prevent complications, treatment needs to begin within the first five days of symptom onset
  • Early treatment is also crucial to prevent “long-haul” symptoms after recovery. None of Zelenko’s patients who started their treatment within the first five days went on to develop long-haul symptoms

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Over-the-counter alternatives to HCQ include EGCG (green tea extract) and quercetin, both of which are zinc ionophores and therefore work much like HCQ does. Quercetin works best when taken in conjunction with vitamin C, however, as the vitamin C helps activate it. Zelenko recommends taking 1,000 milligrams of vitamin C with it.

Now, HCQ does have other mechanisms of action beside being a zinc ionophore, so it’s a better choice, but if you simply cannot get it, EGCG or quercetin are viable stand-ins. Additional benefits of HCQ include:

  • Inhibiting viral entry into the cytoplasm, in part by changing the pH
  • Inhibiting cytokine storms through anti-inflammatory properties
  • Stabilizing red blood cells, which improves oxygenation

“Since it has four different mechanisms of action, it’s a very effective drug, and it has a half-life of 50 days in plasma,” Zelenko says. “But if you can’t get it, you can’t get it. So, I’ll take quercetin or EGCG.”

The caveat here is you must implement this treatment within the right timeframe. It can be helpful to recognize we are in essence dealing with two diseases, or stages of disease, here.

First, there’s the viral infection, and second, there’s the immune over-response that leads to the release of inflammatory cytokines and agents that can cause blood clots. The key is to prevent the progression from the first stage to the second.

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So if you can’t get the “gold standard” drugs (i.e., HCQ; ivermectin), then get quercetin.

It’s available from Puritan’s Pride https://www.puritan.com/quercetin-517/quercetin-plus-vitamin-c-250-mg-700-mg-008039.

Or your an get EGCG https://www.puritan.com/puritans-pride-brand-0102/super-strength-egcg-350-mg-018168?source=igodigital

HEALTH: I am sure you can take Pfizermectin for Covid

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Tired: Ivermectin. Wired: Pfizermectin.

A good chunk of the hostility I’ve received over writing AxisOfEasy (so much that I’ve decided to hand it off to somebody less polarizing) is driven by the coverage of Ivermectin.

It was curious how a few weeks ago the “horse drug” narrative around Ivermectin was suddenly being amplified by the mainstream outlets, despite the fact that it’s an FDA approved drug that’s been used as an anti-parasitic for decades, and the fact that it was being used in India to combat an explosion of Delta Variant.

Now we learn that Pfizer is in clinical trials with PF-07321332, a developmental drug that acts as a “protease inhibitor” against C*V1D-19 for anybody already infected.

Oddly enough that’s exactly the claim made about Ivermectin, that it is a protease inhibitor. People tracking this are euphemistically calling Pfizer’s crack at this, “Pfizermectin.”

Read: https://www.zerohedge.com/covid-19/pfizer-launches-final-study-covid-drug-thats-suspiciously-similar-ivermectin

One wonders if the MSM and Big Tech will conduct a wide-ranging, coordinated campaign of marginalization against Pfizer should Pfizermectin be approved and be deployed.

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Argh!

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HEALTH: Could the Common dandelion help with the WuFlu?

“Well, I’m not a doctor, I have never played one on TV, and I didn’t stay at a Holiday Inn Express last night, but here are some simple thoughts.”

https://www.biorxiv.org/content/10.1101/2021.03.19.435959v1.full

Common dandelion (Taraxacum officinale) efficiently blocks the interaction between ACE2 cell surface receptor and SARS-CoV-2 spike protein D614, mutants D614G, N501Y, K417N and E484K in vitro

Posted March 19, 2021.

This article is a preprint and has not been certified by peer review

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On 11th March 2020, coronavirus disease 2019 (COVID-19), caused by the SARS-CoV-2 virus, was declared as a global pandemic by the World Health Organization (WHO). To date, there are rapidly spreading new “variants of concern” of SARS-CoV-2, the United Kingdom (B.1.1.7), the South African (B.1.351) or Brasilian (P.1) variant. All of them contain multiple mutations in the ACE2 receptor recognition site of the spike protein, compared to the original Wuhan sequence, which is of great concern, because of their potential for immune escape. Here we report on the efficacy of common dandelion (Taraxacum officinale) to block protein-protein interaction of spike S1 to the human ACE2 cell surface receptor. This could be shown for the original spike D614, but also for its mutant forms (D614G, N501Y, and mix of K417N, E484K, N501Y) in human HEK293-hACE2 kidney and A549-hACE2-TMPRSS2 lung cells. High molecular weight compounds in the water-based extract account for this effect. Infection of the lung cells using SARS-CoV-2 spike pseudotyped lentivirus particles was efficiently prevented by the extract and so was virus-triggered pro-inflammatory interleukin 6 secretion. Modern herbal monographs consider the usage of this medicinal plant as safe. Thus, the in vitro results reported here should encourage further research on the clinical relevance and applicability of the extract as prevention strategy for SARS-CoV-2 infection.

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Common dandelion (Taraxacum officinale) efficiently blocks the interaction between ACE2 cell surface receptor and SARS-CoV-2 spike protein D614, mutants D614G, N501Y, K417N and E484K in vitro
Hoai Thi Thu Tran, Nguyen Phan Khoi Le, Michael Gigl, CorinnaDawid, Evelyn Lamy
bioRxiv 2021.03.19.435959; doi:https://doi.org/10.1101/2021.03.19.435959

# – # – # – # – #

Where’s the coverage?

Like that lady doctor in Peru with peroxide, ivermectin, and vitamins, why haven’t we heard about this?  Either positive or negative.

I know Big Pharma ain’t going to make a lot of money off of dandelions either but where are the Gooferment “scientists” studying this — quickly.

I found it via survival blog can’t they.

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INTERESTING: Merck, the company that invented ivermectin, doesn’t want an off-patent drug

https://anti-empire.com/indication-ivermectin-drastically-reduces-deaths-keeps-trickling-in-from-the-third-world-too-bad-its-a-cheap-generic/

Indication Ivermectin Drastically Reduces Deaths Keeps Trickling in From the Third World. Too Bad It’s a Cheap Generic
Would rain on the virus cult parade
Dr. Sebastian Rushworth

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Back in January I wrote an article about four randomized controlled trials of ivermectin as a treatment for covid-19 that had at that time released their results to the public. Each of those four trials had promising results, but each was also too small individually to show any meaningful impact on the hard outcomes we really care about, like death. When I meta-analyzed them together however, the results suddenly appeared very impressive. Here’s what that meta-analysis looked like:

It showed a massive 78% reduction in mortality in patients treated with covid-19. Mortality is the hardest of hard end points, which means it’s the hardest for researchers to manipulate and therefore the least open to bias. Either someone’s dead, or they’re alive. End of story.

You would have thought that this strong overall signal of benefit in the midst of a pandemic would have mobilized the powers that be to arrange multiple large randomized trials to confirm these results as quickly as possible, and that the major medical journals would be falling over each other to be the first to publish these studies.

That hasn’t happened.

*** and ***

I understand why pharmaceutical companies don’t like ivermectin. It’s a cheap generic drug.

Even Merck, the company that invented ivermectin, is doing it’s best to destroy the drug’s reputation at the moment. This can only be explained by the fact that Merck is currently developing two expensive new covid drugs, and doesn’t want an off-patent drug, which it can no longer make any profit from, competing with them.

The only reason I can think to understand why the broader medical establishment, however, is still so anti-ivermectin is that these studies have all been done outside the rich west. Apparently doctors and scientists outside North America and Western Europe can’t be trusted, unless they’re saying things that are in line with our pre-conceived notions.

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Follow the money!

Just like DJT45 said!

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