SARS-CoV-2 infection in hamsters and humans results in lasting and unique systemic perturbations post recovery
JUSTIN J. FRERE
SCIENCE TRANSLATIONAL MEDICINE
7 Jun 2022
The host response to severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection can result in prolonged pathologies collectively referred to as post-acute sequalae of COVID-19 (PASC) or long COVID. To better understand the mechanism underlying long COVID biology, we compared the short- and long-term systemic responses in the golden hamster following either SARS-CoV-2 or influenza A virus (IAV) infection. Results demonstrated that SARS-CoV-2 exceeded IAV in its capacity to cause permanent injury to the lung and kidney and uniquely impacted the olfactory bulb (OB) and epithelium (OE). Despite a lack of detectable infectious virus, the OB and OE demonstrated myeloid and T cell activation, proinflammatory cytokine production, and an interferon response that correlated with behavioral changes extending a month post viral clearance. These sustained transcriptional changes could also be corroborated from tissue isolated from individuals who recovered from COVID-19. These data highlight a molecular mechanism for persistent COVID-19 symptomology and provide a small animal model to explore future therapeutics.
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If this “vaccine”, that should be really called “gene therapy”, had been properly tested, then maybe people would not be panicked, vaccine injured, crippled, or killed unnecessarily.
Maybe it should have been tested on hamsters FIRST!
These ‘invincibles’ have never had COVID — and they want to know why
By Alyson Krueger
January 13, 2022 6:34am Updated
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As COVID cases explode across the US with 62.8 million total reported since 2020, and almost eight million since Jan. 1, 2022 — and even fully vaccinated people reporting breakthrough cases — it seems as if almost no one has been left untouched by the Sars-Cov-2 virus. But like McMullin, there are some who have failed to contract COVID during the entire pandemic, even as Omicron spreads like wildfire.
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Why aren’t we hearing more about these people — what do they eat, what shape are they in, where do they “fit” chemically?
I’ve been convinced for a long time that the “experts” don’t know squat about this.
And the Gooferment politicians and bureaucrats know even less.
One thing is for sure, I KNOW that they don’t have MY best interests at heart.
Thursday, 06 January 2022 10:10 AM
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Europe’s sky is filling up with near-empty polluting planes that serve little other purpose than safeguarding airlines’ valuable time slots at some of the world’s most important airports.
The highly contagious omicron variant of COVID-19 has put many off flying, and because of it, getting people and goods from point A to point B has become an afterthought for thousands of flights. It has created strange bedfellows, with environmentalists and major airlines united to cut down on empty or near-empty flights by pressuring the European Union — a pledged global leader in combating climate change — to tweak the rules on airport slots.
“The EU surely is in a climate emergency mode,” activist Greta Thunberg tweeted sarcastically this week, linking to a story about Brussels Airlines making unnecessary flights.
The company has said that if the EU doesn’t take action, it would have to fly some 3,000 journeys this winter primarily to safeguard its network rights.
German giant Lufthansa said it would have to fly an additional 18,000 “unnecessary” flights through the winter to hold on to landing slots. Even if the holidays brought a big increase in passengers — marked by thousands of flight cancellations that left travelers stranded — the rest of the winter period could be slow as omicron surges worldwide.
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William Rusher, the editor of the conservative National Review, quoted economist Milton Friedman as saying that “if the government were to take over the Sahara Desert, there would be a shortage of sand in five years.”
Ditto, landing slots?
If the airlines could “rent” landing slots from a private entrepreneur, then surely an effective and efficient solution could be found that the didn’t entail flying empty place around at a staggering cost? But once the Gooferment politicians and bureaucrats get involved everyone suffers.